Visualizing Oncolytic Virus-Host Interactions in Live Mice Using Intravital Microscopy
Molecular Therapy Oncolytics, 2018, 10, 14-27. Oncolytic virus (OV) therapy is an emerging cancer treatment that uses replicating viruses to infect and kill tumor cells and incite anticancer immunity. While the approach shows promise, it currently fails most patients, indicating strategies to improve OV activity are needed. Developing these will require greater understanding of OV biology, particularly in the context of OV delivery and clearance, the infection process within


