Comparison of free-radical inhibiting antioxidant properties of carvedilol and its phenolic met
MedChemComm, 2017, 8, 606-615 Carvedilol is a widely prescribed drug for the treatment of heart failure and the prevention of associated ventricular arrhythmias. It has also been reported to function as a biological antioxidant via hydrogen atom transfer from its carbazole N–H moiety to chain-propagating radicals. Metabolites of the drug include phenolic derivatives, such as 3-hydroxy-, 4′-hydroxy- and 5′-hydroxycarvedilol, which are also potential antioxidants. A comparison


